In the field of Industrial Biotechnology, microbial studies of many living organisms such as humans, animals, environment, insects, plants can be carried out on a microbial basis, and in this way, microorganisms are isolated from different sources. In this context, protein, enzyme or other cellular products with microorganism-based biotechnological value can be produced with the help of fermentation technology. In fermentation technology, using microbioreactor systems, medium optimization, optimization of incubation parameters, screening of high yielding cell lines, growth characterization, synthetic and system biology studies, enzyme and cell activity tests, functional genomic, proteomic studies, inhibition and toxicity tests can be performed. Because of the microbiorector system, it is possible to scan the effects of pH, dissolved oxygen, mixing speed, temperature, aerobic/anaerobic conditions by testing 48 different states in parallel. Also, cell growth protocols developed after the optimization studies in the microbioreactor can be transferred to higher volume bioreactors and scale-up processes can be performed in our research center.
One of the most important outputs of Industrial Biotechnology studies is the establishment of successful production conditions for enzymes with different commercial uses and importance. In this process, recombinant protein studies are carried out and the desired target enzyme or protein contents are prepared with the help of molecular techniques and fermentation conditions are started. In our infrastructure center that can carry out R&D and pilot production studies of enzymes with different industrial importance such as agriculture, food, environment and leather, especially clinical.
Another step of Industrial Biotechnology research is the production of different metabolites with the help of microorganisms containing single cell protein technology. In this context, it is possible to produce human and animal food additives, especially by using industrial organic wastes.Among these metabolites, there is the production of vitamin B12, ascorbic acid, the production of different types of amino acids, the production of different organic acids such as pyruvic acid, oxalic acid, fumaric acid, and also the production of new generation antibiotics.